The Chinese herbal concoction RCM-104 is well tolerated and appears to be effective in reducing weight and improving quality of life in obese individuals after 12 weeks.
For further details:
Lenon, G. B., Li, K. X., Chang, Y. H., Yang, A. W., Da Costa, C., Li, C. G., … & Xue, C. C. (2012). Efficacy and safety of a Chinese herbal medicine formula (RCM-104) in the management of simple obesity: a randomized, placebo-controlled clinical trial. Evidence-Based Complementary and Alternative Medicine, 2012.